First check for dirt clinging to the undersides of cylinder bars--this builds up unevenly. If you have chrome plated cylinder bars, you'll sometimes get uneven wear on them due to chrome chipping and this can be on 2 or 3 adjacent bars. If all that looks OK, suggest you back off drive belts on the shoe, fan and rear beater until you've isolated the problem. The center bushings on the shoe actuator arms, if worn, can mimic an out of balance cylinder pretty readily.